Moonlight follows Mick St. John, an immortal vampire and private investigator and his struggle to exist after he was bitten 60 years ago by his vampire bride, Coraline, on their wedding night. It also follows his internal torment as he falls in love with one he should not, one who is mortal named Beth, a news reporter, as well as his dealings with the woman who made him a vampire, his sire Coraline. Josef plays Mick's immortal mentor.

The show is produced by Warner Bros. Television and Silver Pictures. Joel Silver is executive producing with Trevor Munson and Ron Koslow both writing and executive producing.